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However, there is no conclusive evidence to support this advice

Knock down kidney CTR1 by transporting plasmid in UUO To deliver the CTR1-shRNA plasmid in vivo, the UUO rats were randomly divided into four groups: (1) sham, (2) UUO, (3) rats treated with CTR1 shRNA before UUO (shCTR1 + UUO), and (4) rats treated with an empty vector before UUO (shNC + UUO)

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Given the scoping nature of the review and the heterogeneity of available evidence, study selection focused on identifying representative and clinically informative literature rather than exhaustive quantitative inclusion