acetyl l carnitine versus l carnitine Optimum Health L-Carnitine | What is Carnitine?
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Nat Immunol (2001) 2:10978.10.1038/ni1201-1097 8 FoxCJHammermanPSThompsonCB


The main reason is receptor desensitization : continuous stimulation of the same receptor makes cells less responsive over time, so a planned off period lets the receptor resensitize

NT2 cells are immunoreactive to the cholinergic markers choline acetyl-transferase, vesicular acetylcholine transporter, and the non-phosphorylated form of neurofilament H, all indicative of motor neurons
