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doi: 10.1006/bbrc.1996.1550
Zhang Y-Q, Liang Y-K, Wu Y, Chen M, Chen W-L, Li R-H, et al

However, when the allostatic systems are overworked beyond a tipping point , the capacity to respond acutely and appropriately functions poorly and, if the immunologic memory is for an inflammatory or autoimmune response within the nervous system, the shorter-term stress effect could exacerbate into a chronic disease process [357], generating heterogeneous ASD behavioral phenotypes with heterogeneity deriving from interindividual systems differences
Autophagy and apoptosis dysfunction in neurodegenerative disorders
