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In rats with streptozotocin (STZ)-induced diabetes, eight-week treatment with insulin (NPH, 1.5 U/100gr/day) and melatonin (0.2 mg/kg/day in drinking water) improves glucose homeostasis and insulin sensitivity of white adipose tissue comparing with using one of these drugs individually [59]

Prescription diets are formulated for specific medical goals, and adding supplements can unintentionally change the balance that makes them work

doi: 10.1007/s10522-013-9428-5