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Description
This stability is attributed to its unique amino acid composition, which includes multiple proline residues that create conformational constraints resistant to protease activity
Consequently, an alteration of the hepatic ability to synthesize or export GSH has an impact on systemic GSH homeostasis [2]
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To further investigate NFT-dependent activation of Nrf2 and subsequent induction of GCL and glutathione synthesis, protein levels of the respective targets were investigated by Western blotting
