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Alam M, Ali S, Ashraf GM, Bilgrami AL, Yadav DK, Hassan MI
Intrahepatic CPSS generally has poorer prognosis

Additionally, GSVA revealed strong downregulation of inflammation-related pathways such as interferon (IFN), IL6, IL12, and transforming growth factor (TGF ) signaling in both macrophage clusters

Iron-catalyzed lipid peroxidation, along with iron-catalyzed protein nitration, contributes to the induction of the mitochondrial permeability transition and cell necrosis