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As the importance of subcellular metabolite transporters in controlling tumor initiation is poorly understood, it would be interesting to determine whether overexpression or knockout of these transporters is involved in tumorigenesis, metastasis, and immune modulation
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Furthermore, ILC2s accumulate in the choroid plexus of aged mouse brains, and intracerebroventricular transfer of activated ILC2s was found to rejuvenate the aged brain and enhance cognitive function in aged mice, highlighting the lifespan-regulating role of ILC2s in CNS health and aging [137]

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