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425,426,427 These innovative medicines delve deeper into AD mechanisms and present diverse target choices, holding the potential to halt or reverse AD progression

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The loss of astrocytes reduces the density of oligodendrocytes, initiates demyelination, and promotes myelin abnormalities (e.g., decompaction) in the white matter of developing and adolescent mice (7 days to ~1.5-months-old

In addition to thorough medical and family history, a bone age radiograph is the most helpful initial study