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These mechanisms enhance FoxO-driven expression of both classical and noncanonical E3 ligases, robustly activating UPS (Chen K
Zhang XJ, Ji YX, Cheng X, et al
As an antioxidant, GSH plays a fundamental role in regulating the intracellular redox environment, detoxification/quenching of ROS, and supporting oxidative defense (Saharan and Mandal, 2014)
