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Innate Immune Cells, Soluble Products, and Receptors in SSc All innate immune cells and their capacity to be activated in the one hand by pathogen (PAMP) or danger due to tissue damage (DAMP) molecular patterns via PRRs and on the other hand by soluble mediators of inflammation (cytokines, chemokines, lipidic mediators, NO, etc.) participate to SSc pathogenesis
