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Melatonin has yielded histopathologic benefits without consistent short-term EMG improvements, indicating that function may lag behind structure in the early window

doi: 10.1016/S0092-8674(00)81848-6

It remains unclear to which extent the protection mediated by HGF-MET from the excitotoxic insult is mechanistically linked to the protection from other forms of regulated cell death, such as apoptosis and parthanatos