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For readers who want the clinical-outcomes companion to this mechanistic account, the sites overview of what clinical trials indicate about the fat-burning potential of AOD-9604 covers the human efficacy record in more depth

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(PMC) A separate metabolism-focused paper reviewing human trial history makes a similar point: early signals of weight loss were not consistently reproduced in later studies, particularly when intensive diet/exercise protocols were included

10.1016/s1474-4422(12)70238-7 Lancet Neurol