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HDAC2 has been shown to increase the expression of LAPTM4B, leading to the advancement of hepatocellular carcinoma through autophagy [98]
In addition, upregulation of IGFBP2 expression may promote IGF-IR/Akt activation thereby conferring resistance to BRAF and MEK inhibitors [131]
JL, HZ, JZ and XT collected related literature and tabulated it
