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B vitamins: risks for CVD and dementia associated with deficiency, and limited evidence for general population supplementation [1:07:15]

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On the other hand, the evaluated population was based on European centers only, which limits the confidence for extrapolation to other cohorts, because SCA3 patients show high clinical heterogeneity [245]

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Key research areas: Tissue remodeling and extracellular matrix pathways Collagen and decorin synthesis stimulation Gene expression modulation (over 4,000 genes identified) For research purposes only

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