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Table of Contents How Metformin Affects Vitamin B12 Levels Metformin is the first-line pharmacological treatment for type 2 diabetes mellitus in the UK, recommended by NICE for its efficacy in improving glycaemic control with potential cardiovascular benefits in some patients

This is why vitamin B12 deficiency can affect many different organ systems rather than causing just one symptom

In particular, B12 is central to energy production and maintaining processes related to blood and the brain

Coincidental timing is perhaps the most common explanation
