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Table of Contents How Metformin Affects Vitamin B12 Levels Metformin is the first-line pharmacological treatment for type 2 diabetes mellitus in the UK, recommended by NICE for its efficacy in improving glycaemic control with potential cardiovascular benefits in some patients

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This is why vitamin B12 deficiency can affect many different organ systems rather than causing just one symptom

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In particular, B12 is central to energy production and maintaining processes related to blood and the brain

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Coincidental timing is perhaps the most common explanation

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