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4.2.1.3 Liposomes Generally, liposomes are spherical organic nanoparticles with a bilayer lipid structurewhose conventional compositions are mainly characterized as phospholipid and lipids, such as monosialoganglioside, phosphatidylcholines, sphingomyelin, and 1,2-distearoyl-sn-glycero-3-phosphatidyl choline, offering an interior aqueous core and exterior impermeable lipophilic phospholipid layer

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In one embodiment the delivery system is a syringe and needle apparatus that is capable of piercing the tympanic membrane and directly accessing the round window membrane or crista fenestrae cochleae of the auris interna
