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Designed to support the skin's natural repair and regeneration processes, helping improve the appearance of fine lines, texture, tone and overall skin vitality

509 AS-252424 is a specific and targeted ACSL4 inhibitor that binds directly to the glutamine 464 of ACSL4 to inhibit its enzymatic activity, thereby inhibiting lipid peroxidation and ferroptosis, effectively alleviating ferroptosis-mediated organ damage in mouse models, including I/R-induced kidney injury and acute liver injury

Statements Data availability statement The data presented in the study are deposited in the NCBI repository, available at: Author contributions GY: conceptualization, writing-review and editing, and funding acquisition

Maksoud et al