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Both in vivo and in vitro experiments show IGF-2 activates the IGF-1R/PI3K/AKT pathway, reducing apoptosis and inflammation
To elucidate metabolism of ascorbic acid (AsA) in sweet cherry fruit (Prunus avium Hongdeng), we quantified AsA concentration, cloned sequences involved in AsA metabolism and investigated their mRNA expression levels, and determined the activity levels of selected enzymes during fruit development and maturation
In addition, alpha cell mass and glucagon secretion were significantly increased in Taz-KD islets
