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Siebers K, Fink B, Zakrzewicz A, et al
14 The Liver: After passing through the gut wall and entering the portal circulation, the drug is delivered to the liver, which is the body's primary metabolic organ
The goal is to reduce the physiological work required to neutralize and eliminate organic acids, support renal handling of metabolic waste and improve the biochemical terrain in which adenosine, homocysteine and SAH are managed
J Am Heart Assoc.2013;2:e000096 Rayner KJ
