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Description
Another biological process in which the role of glial cells is preponderant and central to MS and other IDDs, is demyelination

In NRK-52E cells, urografin induced apoptosis in a time- and dose-dependent manner and activated an ERS response characterized by increased GRP78/GRP94 expression and PERKeIF2 phosphorylation

This effect typically resolves as the body adjusts to altered metabolic signaling

Clin Microbiol Rev 20:593
