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However, at higher doses or in the presence of oxidative stress and transition metals, curcumin can also interfere with COX-1 activity
For example, a three-month course of lactulose therapy significantly improved sleep quality, reduced daytime sleepiness, and increased sleep duration and REM sleep in patients with minimal HE ( Continuous positive airway pressure is the treatment of choice for OSA, improving sleepiness and potentially benefiting liver health
