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Intracellular Ca 2+ regulates the release of neurotransmitters in the synaptic terminals, thus modulating synaptic activity and plasticity
oxidation of His5, Cys6, Cys7, Tyr16, Phe24, Phe25, and Tyr26
This activity of IRE1 is independent of its role in regulating the UPR and is evolutionarily conserved
