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Herein, we will conclude the role of glutamine metabolic reprogramming in HCC

Cytokine-mediated immune dysregulation: Elevated inflammatory cytokines (e.g., IL-6) during COVID-19 are associated with EBV and may impair immune control of latent virus

This mtDNA can directly bind to and activate NLRP3, triggering its conformational change and oligomerization [223]