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However, analysis of sequencing data from normal populations has reported that typical cysteine changing NOTCH3 mutations are much more common in the general population, with a frequency ranging from one in 1,000 in European populations, to up to one in 100 in certain Far Eastern populations such as Taiwan (360, 361)

Inhibition of NMDA receptor expressed on islet cells can inactivate K ATP channels and ultimately improve blood glucose levels in type 2 diabetic mouse models [185]

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