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That gap, between what is known, what is legal, and what people are already doing, is exactly what the FDA is being asked to close
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For preemptive analgesia, 4 mg/kg of carprofen was given once just before surgery and continued every 24 hours for 3 days postoperatively [2]

Ill also touch on why acetaminophen use in pregnancy and infancy may cause problems due to the infants immature detoxification system