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Thiol-rich antioxidants prevent FA cytotoxicity To address the causal contribution of FA-induced oxidative stress and GSH imbalance to cell death, we set out to test whether FA toxicity could be rescued by the antioxidants NAC, GSH-MEE, or Trolox (water-soluble vitamin E)

A We have measured samples for up to 2 hours

The transported Nrf2 forms a new complex with Maf protein, and induces the transcription of various antioxidant and phase II detoxification enzymes by binding to antioxidant response element (ARE) on DNA

Neuroscientists used to try to understand brain function and dysfunction starting from topographical units (brain areas or brain nuclei) to which they assigned specific functions