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FIGURE 1 DSIP-CBBBP reduces anxiety or depressive-like states Figure 2 delineates the effects of different treatments on locomotor activity in mice within an insomnia model, as assessed by the open field test

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The sst 2a is the receptor most abundantly expressed at this site compared to other subtypes and microinjection of somatostatin into the RVLM induces a sympatho-inhibitory response mimicked by the sst 2 agonist, lanreotide and prevented by an sst 2 antagonist, BIM-23627 in rats (Burke et al., Behavioral responsefocus on food intake Brain CRF receptors are involved in the stress-related reduction of food intake in rodents (Krahn et al., 1986