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Afterwards, bound and total cortisol were determined, and concentrations calculated with a standard curve
distinguished five different subtypes of mCRPC based on RNA expression of AR and the most common neuroendocrine markers: AR-high tumors (ARPC), AR-low tumors (ARLPC), amphicrine tumors with both the expression of AR and NE markers (AMPC), double-negative tumors (DNPC), and tumors with small cell and NE features without AR expression (SCNPC) [40]
These stimulatory chemicals get your body ready for action - what people often call a "fight-or-flight" response
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