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Loss of NADPH oxidase-derived superoxide skews macrophage phenotypes to delay type 1 diabetes

The antioxidant function of Prdx2 also depends on NADPH

Induction of band 3 aggregation in erythrocytes results in anti-band 3 autoantibody binding to the carbohydrate epitopes of band 3

Results Compared with autoantibody negative group, blood pressure, weight, total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), visceral fat mass, fasting C-peptide (FCP), 120 minutes C-peptide (120minCP) and area under C-peptide curve (AUC CP ) of patients in either autoantibody positive or glutamate decarboxylase antibody (GADA) positive group were lower