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QRT-PCR revealed that miR-769-5p expression was significantly reduced, while the expression of Musashi RNA-binding protein 1 (MSI1), a known oncogene, was elevated in CRC tissues and cells compared to controls

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With the progression of MASLD, LSEC undergoes capillarization and hepatic sinusoidal endothelial dysfunction, which gradually shifts from an anti-inflammatory to a pro-inflammatory phenotype and promotes the progression of inflammation, fibrosis and angiogenesis

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