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Earlier studies documented the possible role of these mitochondrial alterations in escalation of metabolic and neurodegenerative disorders including aging, cancer, type 2 diabetes, obesity and dementia [34, 36, 56, 77-88]

We hypothesized that CUL3 binding to ZSWIM8 requires the presence of a folded D-domain

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It is also the leading cause of cancer-related deaths in females in countries with low/medium human development index (HDI)
