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The epigenetic study has found that Hcy induces DNA hypomethylation of the cyclin A promoter by downregulating the expression of DNA methyltransferase 1 (DNMT1) to inhibit endothelial progenitor cells (EPCs) proliferation (108)

It emphasizes underexplored SAR patterns, persistent challenges in achieving isoform-selective inhibition, and emerging opportunities for rational dual-target strategies
BDM1, CYQ2 vs

Xu J, Ahmad A, Jones JF, Dolcetti R, Vaccher E, Prasad U, et al
