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These macrophage-produced cytokines and ROS are involved in the pathogenesis of hypertension-induced endothelial dysfunction and the resulting decreased renal sodium excretion (89)
As we highlighted above with recombinant mAbs, and as shown in historical dengue virus motherinfant data, the theoretical risk of ADE in CP prophylaxis is highest in the weeks following transfusion, when antibody serum neutralization titres fall to sub-protective levels
Methylcobalamin also contains a metal-alkyl bond
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