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Less food consumed means a caloric deficit, which the body addresses by drawing down fat stores

These results imply that GCLC, GSS and SLC7A11 are the potential regulatory targets involved in the VRK2-driven metabolic synthesis pathway of GSH

Metadherin plays an important role in inducing epithelial-mesenchymal transformation (EMT), proliferation, and invasion of tumor cells, promoting treatment resistance and mesenchymal hypercytosis while increasing the vulnerability of tumor cells to ferroptosis inducers, especially GPX-4 inhibitors

Clin Cancer Res 27(16):4587-4598, 2021
