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Immunologically, dialysis exacerbates innate immune dysregulation by promoting oxidative stress-driven NLRP3 activation in circulating monocytes, increasing IL-1 levels
10.1016/j.mib.2024.102473 45 FaldutoM.SmedileF.ZhangM.ZhengT.ZhuJ.HuangQ.et al (2022)
Therefore, we initially set out to identify other GPCRs that might address remaining critical unmet needs for people living with both obesity and T2D
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