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Bacsi A, Aguilera-Aguirre L, German P, Kruzel ML, Boldogh I

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French physician Michel Pistor developed the technique in 1952, and it has been refined over decades of clinical use in aesthetic medicine worldwide

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The KD was also shown to increase anti-inflammatory responses in glaucomatous mice, evidenced by increased expression of Arginase 1, a marker of neuroprotective anti-inflammatory microglia, as well as increased expression of the anti-inflammatory cytokine IL-4 in retinas and optic nerves (40)

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(2022) 55:e13331

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