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Additionally, chronic supplementation has shown potential in ameliorating factors associated with metabolic syndrome and cardiovascular disease, such as arterial hypertension and impaired glucose tolerance.[13] A systematic review and meta-analysis further supports these findings, revealing that L-carnitine supplementation at doses of 13 g/day significantly reduced waist circumference, systolic blood pressure, fasting blood sugar, and triglycerides, while also increasing HDL cholesterol

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Studies have shown that in mice models, TMAO stimulates macrophage recruitment by promoting their migration and expression of TNF-, IL-6 (considered promoters of foam cell formation [79]), as well ICAM1 [80]

Harvesters source kangaroo meat from abundant wild populations in Australia