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However, a multicenter study in 5,485 subjects with cardiovascular disease or diabetes mellitus showed that daily supplementation with folic acid (2.5 mg), vitamin B 12 (1 mg), and vitamin B6 (50 mg) lowered homocysteine concentrations but had no effect on fracture risk compared to placebo (118)

[5] Contraindications & Precautions The primary contraindication for hydroxocobalamin injection is a known hypersensitivity to hydroxocobalamin, cobalt, or any component of the formulation

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Product Composition (Per mL) Methionine 20 mg Inositol 50 mg Choline 50 mg Vitamin B12 (Methylcobalamin) Standard dose (varies per compounder, often 1,000 mcg/mL) Total Volume 30 mL multi-dose vial Form Sterile, preservative-free injectable solution Route of Administration Intramuscular only Compounded to USP standards Storage Refrigerate at 28C Mechanism of Action Lipotropic Complex (MIC) MIC stands for Methionine , Inositol , and Choline a trio of nutrients known for their lipotropic (fat-loving) activity