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The central role of glutathione in the pathophysiology of human disease, 2007 GSH Mitochondrial Transport glutathione and mitochondrial GSH can be transported to mitochondrial matrix by different carriers, particularly the 2-oxoglutarate carrier (OGC) and the dicarboxylate carrier (DIC), located in the mitochondrial inner membrane

cis -DDP, cisplatin

AIs can be divided into two groups based on their chemical structure: steroidal (analogs of androstenedione, exemestane, formestane, and testolactone), which provide irreversible aromatase inhibition, and non-steroidal (anastrozole and letrozole), which provide reversible inhibition (Ahmad, 2015)

Tested in ELISA, Flow Cytometry, IHC, WB applications