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Description
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HNE inhibits inflammasome activation by blocking the NLRP3-NEK7 interaction via a cysteine-dependent mechanism The family of mammalian NIMA-related kinases 7 (NEK7) was recently identified as an NLRP3-binding protein that regulates NLRP3 oligomerization and activation (44-47)

Both are used in advanced peptide-based formulations

It is commonly used as part of a skin detox treatment plan to support both wellness and skin clarity
