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A deficiency in Vitamin B12 can lead to fatigue, weakness, and even neurological complications

Yearly monitoring of B 12 status and suitable adjustment of the supplementation dose is recommended.50 For symptomatic deficiency (box 1) caused by insufficient dietary intake, intramuscular B 12 therapy is usually initiated with the aim of progressing to oral supplements once symptoms have resolved.789 Symptomatic deficiency in people with B 12 malabsorption Suggested treatment schemes differ considerably between countries

Possible effects include: reduced fat storage increased metabolic activity Further human research is needed

Full results can take up to 23 months