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It is often paraneoplastic (small cell lung cancer) and causes extreme sensitivity to non-depolarizing neuromuscular blockers
We also constructed an M25AD ADC using monomethyl auristatin E (MMAE) and obtained potent inhibition of mesothelioma xenografts in vivo at a dose of 3 mg/kg (Figure 4)
The laser-on time was set to 20 s and with data being recorded for two seconds prior to the laser being turned on and for 2 s post being turned off
Parkinson-causing -synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation
