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Subsequently, AA-PE and AdAPE are oxidized by 15-lipoxygenase (15-LOX) to produce lipid hydroperoxide, which ultimately leads to ferroptosis (Gao and Jiang, 2018), and further research finds that ferroptosis is initiated by the selective and specific peroxidation of sn2-ETE-PE to sn2-15HpETE-PE by 15-LOX/PEPB1 complex (Kagan et al., 2017
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It can also help with fatigue, nerve problems, and other side effects
Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota
