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Although we may not have sufficient power to detect significant changes in our secondary outcomes (tau PET, MRIs, CSF AD biomarkers and cognition), including a nine-month follow-up will help provide preliminary evidence of successful modification of disease trajectory over a one-year period

This is an important aspect to consider in in-vivo studies on the pharmacokinetics and metabolism of MDPs in the inner ear

Upon phosphorylation, these transcription regulators are hypothesized to enter the nucleus of somatotroph cells, potentially affecting the genes that govern growth hormone production

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