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For example, advanced oxidation protein products (AOPP), total oxidant status (TOS), and oxidative-stress index (OSI) have been found to be elevated in MASLD patients and correlated with disease severity [128]

These findings suggest that vitamin B1 supplementation may offer potential therapeutic strategies for improving brain function in LLD patients by synergistically regulating energy metabolism and inflammatory responses

[DOI] [PubMed] [Google Scholar] 32.Snchez S, Aguilar RP, Genta S, Aybar M, Villecco E, Riera AS

TGF1-induced suppression of glutathione antioxidant defenses in hepatocytes: Caspase-dependent post-translational and caspase-independent transcriptional regulatory mechanisms