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Eur J Clin Nutr

While the implications for SARM1 in regulating axonal fate are well-established, the sensing mechanisms of this protein complex toward NAD + , NMN, or even possibly toward other NAD + metabolites are not fully understood, and may suggest that also the other NAD + metabolites could regulate more biological processes than initially thought 54

This underscores why unexplained elevations, particularly above 1,000 pg/mL, should be taken seriously and investigated
