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For the annulus fibrosus (the outer ring of the disc made primarily of collagen), this mechanism may support healing of small tears and prevent further deterioration

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Li J, You S, Zhang S, Hu Q, Wang F, Chi X, Zhao W, Xie C, Zhang C, Yu Y (2019) Elevated N-methyltransferase expression induced by hepatic stellate cells contributes to the metastasis of hepatocellular carcinoma via regulation of the CD44v3 isoform