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LDF signals were sampled at 1 kHz by an LDF spectrometer (PeriFlux System 5000, PERIMED, Sweden) and digitally acquired through a Plexon system

However, TMRE staining is increased in atfs-1(null) worms when nhr-180 is knocked by RNAi to levels comparable to wildtype worms (Fig

Thus, although GTK probably contributes to the bioactivation of toxic halogenated cysteine S -conjugates in the rat kidney, other cysteine S -conjugate -lyases presumably play an important role in the mitochondrial damage

Such reactions will subtract RNS from critical cellular targets, such as cell membrane lipids and proteins belonging to the complexes of the electron transport chain, thereby explaining why GSH status appears to be so critical in modulating the susceptibility to NO