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Mller (0.5 10 4 cells/well) and BV-2 cells (5 10 4 cells/well) were cultured in 96-well cell culture plates in media containing various concentrations of GSSSG (Kyowa Hakko Bio, Tokyo, Japan) or LPS (Sigma-Aldrich, St
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It is, mechanistically, a direct intervention on the same signalling pathway that underlies the metabolic inflammation that made weight loss difficult in the first place

Commercial development was terminated in 2007