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Dagnino-Leone J, Figueroa CP, Castaeda ML, Youlton AD, Vallejos-Almirall A, Agurto-Muoz A, et al

The human glutathione synthetase enzyme is a homodimer with a subunit size of 52 kDa

Consequently, MEL, through its interaction with MT1 and MT2 receptors, can regulate cellular processes like oxidative stress, antioxidant enzyme activity, inflammation, and apoptosis, thereby offering protective effects on health

After wounding or UVR, Endothelin 1 (EDN1)/EDNRB signaling enhances the proliferation and differentiation of McSC and increases the regeneration of epidermal melanocytes 22 , 35